VThunter

Pangolin

Scientific Name: Manis javanica

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Pholidota-> Manidae-> Manis

Simian immunodeficiency virus

Family: Reoviridae

Receptor: CD4

Receptor CD4 information

Summary: This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020] [NCBI] [Proteinatlas]

Data Source

Data set information

Project	Date	Technology	Tissue	Condition	Cell	PMID/DOI
Vthunter_0036	2021.04	10X Genomics	Esophagus	Normal	24581	Link
Vthunter_0037	2021.04	10X Genomics	Heart	Normal	12958	Link
Vthunter_0038	2021.04	10X Genomics	Kidney	Normal	4481	Link
Vthunter_0039	2021.04	10X Genomics	LargeIntestine	Normal	3328	Link
Vthunter_0040	2021.04	10X Genomics	Liver	Normal	5694	Link
Vthunter_0041	2021.04	10X Genomics	Lung	Normal	13720	Link
Vthunter_0042	2021.04	10X Genomics	Spleen	Normal	3207	Link
Vthunter_0043	2021.04	10X Genomics	Stomach	Normal	12485	Link